General Cell Based Assays
Cayman Chemical EstradIol 3 DGlucuronIde 5mg
A non-cholestatic regioisomer of E217G that acts as a substrate for MRP2, competing with E217G for MRP2-mediated transport (IC50 = 14.2 µM)
Meso Scale Discovery R-PLEX Human hCG alpha ASY
The R-PLEX Human HCG Alpha Assay Kit from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for measuring human chorionic gonadotropin alpha subunit (hCG ) in various biological matrices It uses MSD s SULFO-TAG labels and multi-array plate technology for sensitive detection The kit includes a 96-well plate with capture antibody detection antibody with ruthenium label calibrators and diluent Sensitivity is 0 05 mIU/mL with an upper limit of 1000 mIU/mL suitable for monitoring hCG levels and pregnancy testing
Electron Microscopy Sciences Flim Sleeve 135 mm/24 exp with Frosted Open Flap
Polyguard Polypropylene film sleeves are the finest archival quality material, and are guaranteed to give you ultimate protection for your most important film negatives. Polyguard is 100% acid free, as well as being free from optical distortion. It is resistant to water, grease, oil, alkalies, and organic solvents. Polyguard is durable, yet pliable and gentle to the film and will not become brittle, crack, or abrade the film.
Type: Frosted Open Flap
Cell Biolabs Inc Free Fatty Acid Assay Kit (Colorimetric), 100 assays
Free fatty acids (FFA) are formed from the hydrolyisis of triglyceride ester bonds and serve as a ready energy source by binding to albumin in the bloodstream. Measurement of FFA has become an important part of monitoring various disease states including obesity, diabetes, and cancer. Cell Biolabs' Free Fatty Acid Assay Kit quantifies the FFA concentration (non-esterified) in various samples using a 96-well colorimetric plate format. It can detect FFA levels as low as 15 µM in plasma or serum samples. Each kit provides sufficient reagents for 100 assays including standards and unknown samples.
ABclonal Technology TrKC Rabbit pAb
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
Eurofins Discoverx AssayComplete Cell Plating 43 Reagent, 100. (93-0563R43A)
AssayComplete Cell Plating 43 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress ACVRL1/BMPR2 Dimerization Assay, 10pl Kit. (93-0962E3CP22L)
The PathHunter ACVRL1/BMPR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. GDF2/BMP9) induced dimerization of ACVRL1/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses ACVRL1 target protein fused to PK alongside BMPR2 target protein fused to EA. Upon ligand-induced dimerization of ACVRL1/BMPR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress C5AR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0079E2CP2M)
The cAMP Hunter C5AR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. C5a) based activation of C5AR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type C5AR1, a naturally Gi/Go coupled GPCR. Upon activation of C5AR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Enzo Life Sciences Catalase fluorometric detection kit (500tests)
The Catalase fluorometric detection kit provides a higher throughput sensitive method for measuring catalase activity in just one hour. This is a homogeneous mix-and-read assay that enables you to monitor multiple time points for a kinetic read. Positive control is provided. Sensitivity: (range 0- 4 U/ml). UniProt ID: P00432. Applications: Fluorescent detection, HTS . Species reactivity: Species independent . Content: Reaction buffer concentrate, Detection Reagent, Horseradish peroxidase concentrate, Hydrogen peroxide, Catalase enzyme.
Eurofins Discoverx cAMP Hunter eXpress FFAR3 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0136E2CP2L)
The cAMP Hunter FFAR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. FFAs) based activation of FFAR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FFAR3, a naturally Gi/Go coupled GPCR. Upon activation of FFAR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery VPLEX Plus GLP1 Total
The Meso Scale Discovery V-PLEX Plus GLP-1 Total Kit is an electrochemiluminescent immunoassay for the quantitative measurement of total glucagon-like peptide-1 (GLP-1) in human serum plasma and culture media samples The kit contains a 96-well plate coated with a GLP-1 specific capture antibody a ruthenium-labeled detection antibody calibrators controls assay diluent read buffer wash buffer and plate seals The assay has a range from 0 61 pg/mL to 5000 pg/mL and takes approximately 3 5 hours to complete This product allows for the sensitive and accurate quantification of total GLP-1
Meso Scale Discovery R-PLEX Rat MIP-3 ASY
The R-PLEX Rat MIP-3alpha Assay Kit from Meso Scale Discovery is a multiplex immunoassay for measuring rat MIP-3alpha in various biological fluids It uses MSD s electrochemiluminescent detection for high sensitivity and a wide dynamic range with low sample volume An MSD instrument like QuickPlex is needed to read the plate The kit includes a 96-well plate with capture and detection antibodies plus calibrators and controls Detection limits are 1 52 pg/mL to 1500 pg/mL for rat MIP-3alpha
TRIBIOSCIENCE INC β-Glucuronidase Assay 100 Tests
Tribioscience’s β-Glucuronidase Activity Colorimetric Assay provides a simple and sensitive method for monitoring glucuronidase activity in biological samples (tissue, cells, serum, urine). This assay uses a synthetic p- nitrophenol derivative (R-pNP) as its substrate. The substrate releases a chromophore pNP under β-Glucuronidase, which can be measured at absorbance (OD 405 nm). The assay can detect as low as 50 µU of glucuronidase activity in a variety of samples.
Meso Scale Discovery R-PLEX Human BMP-4 ASY
The R-PLEX Human BMP-4 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures the concentration of human Bone Morphogenetic Protein 4 (BMP-4) in serum plasma and cell culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer calibrator and control The assay has a typical sensitivity of 0 3 pg/mL and an upper limit of quantification of 10 000 pg/mL